[3P-270] Metabolic change affects susceptibility to ferroptosis in cancer cells

^○Seiji Torii¹, Chisato Kubota^1,2 (1.Gunma University Center for Food Science and Wellness (GUCFW), 2.Research Fellow of Japan Society for the Promotion of Science)

The 92nd Annual Meeting of JBS

[3P-271] Roles for Hippo signaling pathway in cervical cancer

^○Tomohiko Maehama¹, Miki Nishio¹, Yoko To², Tohru Kiyono³, Hironori Tashiro⁴, Akira Suzuki^1,5 (1.Div. of Mol. and Cell. Biol., Grad. Sch. of Med., Kobe Univ., 2.Dept. of Obst. and Gynecol., Faculty of Life Sci., Kumamoto Univ., 3.Div. of Carcinogenesis and Cancer Prevention, Natl. Cancer Res. Inst., 4.Dept. of Maternal-Newborn Nursing, Sch. of Health Sci., Kumamoto Univ., 5.Med. Inst. Bioreg., Kyushu Univ.)

The 92nd Annual Meeting of JBS

[3P-272] Protein knockdown system targeting YAP in malignant mesothelioma

^○Waka N. Nagano¹, Rie K. Kawamoto¹, Kazuo H. Hukuda², Takuji S. Syoda³, Ryu Y. Yamazaki², Takahisa N. Nakane⁴, Iwao O. Okamoto², mikihiko N. Naito⁵, Naoko N. Nakano¹, Susumu I. Ito¹ (1.Laboratory of Biochemistry, Showa Parmaceuticai University, 2.Laboratory of Pharmaceutical Organic Chemistry, Showa Parmaceuticai University, 3.Division of Organic Chemistry, National Institute of Health Science, 4.Laboratory of Natural Products Chemistry, Showa Parmaceuticai University, 5.Division of Molecular Target and Gene Therapy Products, National Institute of Health Science)

The 92nd Annual Meeting of JBS

[3P-273] Exploration of cellular signaling pathways which crosstalk to the poly(ADP-ribose) catabolic system

^○Takahiro Oyama¹, Yuki Yahagi², Yuto Shibui², Hideaki Abe¹, Fumiaki Uchiumi², Sei-ichi Tanuma³ (1.Hinoki Shinyaku Co., Ltd., 2.Fac. Pharm. Sci., Tokyo Univ. Sci., 3.Dept. Genom. Med.Sci., Res. Inst. Sci. Tech., Tokyo Univ. Sci.)

The 92nd Annual Meeting of JBS

[3P-274] Suppression of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-β signaling

^○Risako Azuma¹, Teppei Shibasaki¹, Keigo Sano¹, Shouei Amano¹, Yutaro Sawada¹, Ryo Ishikawa¹, Fumiko Itoh², Yukihide Watanabe³, Makoto M. Taketo⁴, Mitsuyasu Kato³, Susumu Itoh¹ (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Laboratory of Experimental Phathology, University of Tsukuba, 4.Division of Experimental Therapeutics Graduate School of Medicine Kyoto University)

The 92nd Annual Meeting of JBS

[3P-275] Mechanistic analysis of promotion of invasion mediated by FABP5 - EDIL3 pathway inprostate cancer cells

^○Akira Ando¹, Shogo Senga², Hiroshi Fujii³ (1.Dept.of Biomed. & Eng., Interdisci.Grad.Sch of Sci. & Technol., Univ.of Shinshu, 2.Dept.of Bioscience & Food Production, Interdisci.Grad.Sch of Sci. & Technol., Univ.of Shinshu, 3.Department of Biomolecular Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University)

The 92nd Annual Meeting of JBS

[3P-276] LncRNA S181022 acts as an oncogene in non-small cell lung cancer through influencing STRN3 expression

Ri Sho¹, ^○Xuhong Zhang², Ken Hamada³, Hirohiko Tachibana⁴, Tsukasa Osaki¹, Masayoshi Souri¹, Tsuneo Konta¹ (1.Department of Public Health & Hygiene, Yamagata University Graduate School o f Medical Science, 2.Department of Biochemistry and Molecular Biology, Yamagata University Graduate School of Medical Science, 3.Department of Surgery II, Yamagata University Faculty of Medicine, 4.Department of Dentistry, Oral and Maxillofacial Surgery, Yamagata University Faculty of Medicine)

The 92nd Annual Meeting of JBS

[3P-277] Establishment and molecular characterization of human mesothelial cells disrupting NF2 and CDKN2A using the CRISPR/Cas9system

^○Sivasundaram Karnan, Akinobu Ota, Toshinori Hyodo, Hiroyuki Konishi, Shinobu Tsuzuki, yoshitaka Hosokawa (:Dept.of Biochem. Aichi Med. Univ. of Medicine)

The 92nd Annual Meeting of JBS

[3P-278] Biological activity of galectin-4 and its roles in colorectal cancer cells growth.

^○Takashi Ogawa¹, Yasuhiro Nonaka¹, Hiroki Shoji², Nozomu Nishi³, Takanori Nakamura¹ (1.Dept. of Endocrin., Faculty of Med., Kagawa Univ., 2.Dept. of Biol., Kanazawa Med. Univ., 3.Life Sci. Res. Center, Kagawa Univ.)

The 92nd Annual Meeting of JBS

[3P-279] Evaluation of cell growth inhibition by azolato-bridged dinuclear platinum(II)complexes in human prostate cancer cells

^○Tasuku Arai¹, Takeshi Matsunaga¹, Maya Kamao², Seiji Komeda³, Yoshihisa Hirota¹ (1.Department of Bio-science and Engineering, College of Systems Engineering and Science, Shibaura Institute of Technology, 2.Extension center, Kobe Pharmaceutical University, 3.Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science)

The 92nd Annual Meeting of JBS