[3P-220] NDRG1 functions as a critical activator for VEGF-A-induced angiogenesis by PLCγ/ERK signal activation in vascular endothelial cells

^○Kosuke Watari¹, Tomohiro Shibata¹, Ai Shinoda¹, Hideaki Fujita², Akihiko Kawahara³, Yuichi Murakami^1,4, Michihiko Kuwano⁴, Mayumi Ono¹ (1.Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, 2.Faculty of Pharmaceutical Sciences, Nagasaki International University, 3.Department of Diagnostic Pathology, Kurume University Hospital, 4.Cancer Translational Research Center, St. Mary's Institute of Health Sciences)

The 92nd Annual Meeting of JBS

[3P-221] Swiprosin-1 is involved in the LPS-induced TNF-α production signal of macrophage cell line RAW264.7

^○Tatsuo Katagiri, Makoto Ogawa, Nonoka Wakabayashi (Dept. Pharm Biology. U-toyama)

The 92nd Annual Meeting of JBS

[3P-222] Mechanisms of HSF1-mediated mitochondrial unfolded protein response

Katiyar Arpit, Mitsuaki Fujimoto, Ryosuke Takii, Pratibha Srivastava, Mariko Okada, ^○Akira Nakai (Dept. of Biochem. & Mol. Biol., Grad. Sch. of Med., Yamaguchi Univ.)

The 92nd Annual Meeting of JBS

[3P-223] Calcium-mediated transient upregulation of Sema3A in normal human epidermal keratinocytes is regulated via MAPK/AP-1 signaling pathway

^○Yayoi Kamata^1,2, Mitsutoshi Tominaga^1,2, Yoshie Umehara³, Kotaro Honda¹, Kenji Takamori^1,2 (1.Inst. for Env. and Gen. Med, Juntendo Univ. Grad.Sch. of Med., 2.Anti-Aging Skin Research Laboratory, Juntendo Univ. Grad.Sch. of Med., 3.Atopy Research Center, Juntendo Univ, Grad.Sch. of Med.)

The 92nd Annual Meeting of JBS

[3P-224] Heme-signal regulates phosphorylation dynamic in disordered region and interacting proteins of transcription factor BACH2

^○Miki Matsui¹, Shun Kadoya¹, Hiraki Shima¹, Akihiko Muto¹, Mitsuyo Matsumoto¹, Mikako Shirouzu², Kazutaka Murayama^2,3, Kazuhiko Igarashi¹ (1.Dep.of Biochem.Tohoku Univ., 2.RIKEN Center for Biosystems, Dynamics Research (RIKEN, BDR), 3.Sch. of Biomed. Engi., Tohoku)

The 92nd Annual Meeting of JBS

[3P-225] Identification and functional analysis of transcriptional regulators for ChREBP in pancreatic β cells

^○Atsushi Yokoyama¹, Erika Noro¹, Takuro Matsuzawa², Takeo Yoshikawa², Hiroki Shima³, Kazuhiko Igarashi³, Akira Sugawara¹ (1.Department of Molecular Endocrinology, Graduate School of Medicine, Tohoku University, 2.Department of Pharmacology, Graduate School of Medicine, Tohoku University, 3.Department of Biochemistry, Graduate School of Medicine, Tohoku University)

The 92nd Annual Meeting of JBS

[3P-226] Homeobox protein Hex regulates the transcription of L-type pyruvate kinase

Moe Ono, ^○Takashi Tanaka, Miki Yamada, Koji Tomita (faculty of Pharm., Osaka Ohtani Univ.)

The 92nd Annual Meeting of JBS

[3P-227] Transcription factor GATA2 is essential for development of adrenal chromaffin cells

Tomomi Asaka¹, Yoshiko Kawai¹, ^○Takashi Moriguchi² (1.Tohoku Medical and Pharmaceutical University, Div. Physiology, 2.Tohoku Medical and Pharmaceutical University, Div. Medical Biochemistry)

The 92nd Annual Meeting of JBS

[3P-228] Functional analysis of activation domain of transcription factor Sp1

^○Jun Kuwahara¹, Kumiko Onishi¹, Chisana Uwatoko¹, Katsumi Matsuzaki², Masaru Hoshisno² (1.Faculty of Pharmaceutical Sciences, Doshisha Women's University, 2.Graduate School of Pharmaceutical Sciences, Kyoto University)

The 92nd Annual Meeting of JBS

[3P-229] Analysis of oxidative stress related factors and transcriptional regulators in spontaneously hypertensive rats (SHRs)

^○Mebuki Yamada, Kazuhiko Yamamoto (Kinki University Graduate School of System Engineering)

The 92nd Annual Meeting of JBS