[2T16m-02] Functional analysis of pyrrolated proteins

^○Miho Chikazawa¹, Shiori Iwata¹, Masanori Itakura¹, Eita Sasaki¹, Koji Uchida^1,2 (1.Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.AMED-CREST)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:20 AM - 11:30 AM

[2T16m-03] Oxidized vitamin C-modified protein regulates macrophage function

^○Masanori Itakura¹, Lumi Negishi², Miho Chikazawa¹, Eita Sasaki¹, Koji Uchida^1,3 (1.Laboratory of Food Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.Central Laboratory, Institute for Quantitative Biosciences, The University of Tokyo, 3.AMED-CREST)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:30 AM - 11:40 AM

[2T16m-04] Pathophysiological functions of mitocryptide-2, a novel neutrophil-activating peptide derived from mitochondrial cytochrome b

^○Yoshito Takamuro, Takenori Yamada, Tatsuya Hattori, Hiroki Morikawa, Naoyuki Tamura, Yoshiaki Kiso, Hidehito Mukai (Laboratory of Peptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:40 AM - 11:50 AM

[2T16m-05] Innate immune response in primary microglial cells from abcd1-deficient mice

^○Taiki Yoda, Taro Kaizawa, Mayu Oishi, Masashi Morita, Takanori So (Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:50 AM - 12:00 PM

[2T16m-06] Pro-inflammatory gene programming of histamine H3 receptor agonism in a mouse model of cardio-renal association

^○Naoto Muromachi¹, Junji Ishida², Kazuyuki Noguchi², Jun-Dal Kim², Akiyoshi Fukamizu² (1.Graduate School of Comprehensive Human Sciences, University of Tsukuba, 2.Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 12:00 PM - 12:10 PM

[2T17m-01] Sema4D deficiency-induced changes in arginine metabolism promote microglial proliferation in MCAO mice

^○Toshinori Sawano¹, Ryo Tsuchihashi², Natsumi Yamaguchi¹, Jin Nakatani¹, Shinobu Inagaki², Hidekazu Tanaka¹ (1.Laboratory of Pharmacology, Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, 2.Group of Neurobiology, Division of Health Sciences, Graduate School of Medicine, Osaka University)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:10 AM - 11:20 AM

[2T17m-02] Galectin 3 binding protein suppresses Aβ production via modulation of endogenous β-secretase activity

^○Tsuneyoshi Seki¹, Motoi Kanagawa¹, Kazuhiro Kobayashi¹, Hisatomo Kowa², Naoki Yahata^3,6, Kei Maruyama⁴, Nobuhisa Iwata⁵, Haruhisa Inoue^6,7,8, Tatsushi Toda^1,9 (1.Division of Neurology/Molecular Brain Science, Kobe University Graduate School of Medicine, 2.Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, 3.Department of Anatomy I, Fujita Health University School of Medicine, 4.Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 5.Department of Genome- based Drug Discovery, Graduate School of Biomedical Sciences, Nagasaki University, 6.Center for iPS Cell Research and Application (CiRA), 7.iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center (BRC), 8.Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), 9.Department of Neurology, Graduate School of Medicine, The University of Tokyo)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:20 AM - 11:30 AM

[2T17m-03] The regulatory mechanism of ApoE expression via SphK2/S1P signaling

^○Masato Komai, Yuka Noda, Takashi Uehara, Nobumasa Takasugi (Dept. Medicinal Pharmacol., Grad. Sch. Med. Den. Pharmaceutical sci, Okayama Univ.)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:30 AM - 11:40 AM

[2T17m-04] the regulation of Amyloid β degradation by GPR120

^○Kazunori Kikuchi, Kiwami Kidana, Yukiko Hori, Taisuke Tomita (Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:40 AM - 11:50 AM

[2T17m-05] MITOL prevents AD pathology by increasing Aβ oligomer aggregation

^○Mikihiro Mitsubori, Hiroko Iwasaki, Keisuke Takeda, Ryoko Inatome, Shigeru Yanagi (Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences)

The 92nd Annual Meeting of JBS |Thu. Sep 19, 2019 11:50 AM - 12:00 PM