[1P-322] Involvement of sphingolipid metabolism in the pathophysiological mechanism of schizophrenia

^○Kayoko Esaki¹, Akiko Watanabe¹, Yoshimi Iwayama², Chie Shimamoto¹, Yoshio Hirabayashi³, Brian Dean⁴, Takeo Yoshikawa¹ (1.RIKEN, Center for Brain Science, Lab. for Molecular Psychiatry, 2.RIKEN, Center for Brain Science, Support Unit for Bio-Material Analysis, 3.Juntendo Univ., Institute for Environmental and Gender Specific Medicine, 4.The Florey Institute of Neuroscience and Mental Health, Australia)

The 92nd Annual Meeting of JBS

[1P-323] Infantile leukoencephalopathy-associated C11orf73 mutant proteins are contained in the lysosome whose signaling is downregulated, inhibiting oligodendroglial differentiation

^○Kohei Hattori, Junji Yamauchi (Tokyo University of Pharmacy and Life Sciences Laboratory of Molecular Neuroscience and Neurology)

The 92nd Annual Meeting of JBS

[1P-324] Atypical hypomyelinating leukodystrophy 3-associated mutations of AIMP1 lead to inhibition of neuronal differentiation.

^○Yu Takeuchi, Jyunji Yamauchi (Laboratory of Molecular Neuroscience and Neurology)

The 92nd Annual Meeting of JBS

[1P-325] X11-like regulates uptake of ApoE by modulating intracellular trafficking of Lrp8.

^○Keiko Honda, Megumi Tokyoda, Jialing Guo, Tadashi Nakaya, Toshiharu Suzuki (Laboratory of Neuroscience, Faculty of Pharmaceutical Sciences, Hokkaido University)

The 92nd Annual Meeting of JBS

[1P-326] Intracerebral amyloid plaque change by p3-Alc beta peptide administration to a mouse model of Alzheimer's disease

^○Shoichi Kinoshita¹, Haruka Saito¹, Takashi Saito², Takaomi Saido², Toshiharu Suzuki¹, Saori Hata¹ (1.Hokkaido University, Graduate School of Pharmaceutical Sciences, Neuroscience, 2.RIKEN Center for Brain Science, Laboratory for Proteolytic Neuroscience)

The 92nd Annual Meeting of JBS

[1P-327] Neuronal Toxicity by ALS-related Sigma-1 Receptor Missense Mutation

^○Yasuharu Shinoda, Hideaki Tagashira, Kohji Fukunaga (Dept Pharmacol, Tohoku Univ Grad Sch Pharm Sci)

The 92nd Annual Meeting of JBS

[1P-328] Rab11-mediated regulation of cell surface expression of MHC class II in dendritic cells

Yuka Sato¹, Takumi Furuta¹, Mahiro Kuroda¹, Satoshi Tanaka², ^○Kazuyuki Furuta¹ (1.Dept. Immunobiol., Okayama Univ. Grad. Sch. Med., Dent., Pharmac. Sci., 2.Dept. Pharmacol., Kyoto Pharmac. Univ.)

The 92nd Annual Meeting of JBS

[1P-329] Thp-1 phagocytic ability promoting effect by yeast

^○Astuko Miura, Kei Itou, Shun Matutani, Sinya Kawate, Yosihito Hosaka, Hideaki Itou (Akita Graduate School Faculty of Science and Engineering Technology Department of Life Science)

The 92nd Annual Meeting of JBS

[1P-330] Importance of SIRPα⁺ dendritic cells for the development of fibriblastic reticular cells of peripheral lymph nodes

^○Satomi Komori, Yasuyuki Saito, Datu Respatika, Taichi Nishimura, Takenori Kotani, Yoji Murata, Takashi Matozaki (Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan)

The 92nd Annual Meeting of JBS

[1P-331] Effects of food allergy vaccine on food allergy model mouse induced by cutaneous sensitization

^○Etsuhisa Takahashi¹, Takako Sawabuchi¹, Takao Fujisawa², Mizuho Nagao², Takashi Kimoto¹, Keiko Kameda^1,2, Satoko Sakai¹, Hiroshi Kido¹ (1.Tokushima University, Institute for Enzyme Research Division of Pathology and Metabolome Research for Host Defense, 2.Mie National Hospital, National Hospital Organization)

The 92nd Annual Meeting of JBS