[1P-0482] Knockdown of Golgi stress-responsive caspase-2 ameliorates HLD17-associated AIMP2 mutant-mediated inhibition of oligodendroglial cell morphological differentiation

^○Arisa Ochiai, Junji Yamauchi (Mol.Neurology.Lab., TUPLS)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0483] Impairment ER-Golgi trafficking via ER calcium depletion as a cellular pathogenesis of Pelizaeus-Merzbacher Disease

^○Heng Li, Yuichi Goto, Ken Inoue (Dept. of Mental Retardation and Birth Defect Research, NCNP)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0484] Hypomyelinating leukodystrophy 15-associated mutation of EPRS1 results in polymeric aggregation in the Rab7-positive vesicles, inhibiting oligodendrocyte differentiation

^○Mizuki Goto, Junji Yamauchi (Mol.Neurology.Lab., TUPLS)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0485] Neuroprotective effect of vitronectin, an extracellular matrix protein, in recovering from traumatic brain injury.

^○Minori Yamashita^{1, 2}, Kei Hashimoto³, Mari Nakashima^{1, 2}, Hiroko IkeshimaKataoka⁴, Yasunori Miyamoto^{1, 2} (1.Institute for Human Life Innovation, Ochanomizu University, 2.Graduate School of Humanities and Sciences, Ochanomizu University, 3.Academic Production, Ochanomizu University, 4.Faculty of Science and Engineering, Waseda University)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0486] A new adoptive transfer model for neuromyelitis optica spectrum disorders (NMOSD)

^○Chika Omatsuzawa^{1, 2}, Simon Chau², Yoshiki Miyasama³, Mikako Hirose¹, Mito Asano¹, Tomoji Mashimo⁴, Hidemi Misawa¹, Masato Yasui², Yoichiro Abe² (1.Div. of Pharmacol., Faculty of Pharm., Keio Univ., 2.Dept. of Pharmacol., Sch. of Med., Keio Univ., 3.Inst. Exp. Animal Sci., Osaka Univ. Med. Sch., 4.Lab. Animal Res. Center, Inst. of Med. Sci., Univ. of Tokyo)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0487] Analysis of the role of CCL20 in the development of multiple sclerosis using CCL20-deficient mice

^○Nozomi Sachi, Naganori Kamiyama, Benjawan Saechue, Sotaro Ozaka, Astri Dewayani, Shimpei Ariki, Thanyakorn Chalalai, Yasuhiro Soga, Chiaki Fukuda, Takashi Kobayashi (Department of Infectious Disease Control, Oita University Faculty of Medicine.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0488] Resveratrol, SIRT1 activator, promotes membrane repair of C2C12 cells.

^○Naotoshi Iwahara, Atushi Kuno, Ryusuke Hosoda (Dept. of Pharma. Sapporo Med)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0489] Effect of Cyclic Phosphatidic Acid (2ccPA) on Microglial Polarization During Traumatic Brain Injury

^○Rino Takei¹, Mari Nakashima¹, Mari Gotoh², Misaki Endo¹, Yasunori Miyamoto^{1, 2}, Kimiko MurakamiMurohushi³ (1.Div. of Life Sci., Grad. Sch. of Humani and Sci., Ochanomizu Univ. Otsuka, Bunkyo-ku, Tokyo, Japan, 2.Inst. of HLI, Ochanomizu Univ., Otsuka, Bunkyo-ku, Tokyo, Japan, 3.Res. Div. of Human Welfare Sci., Ochanomizu Univ., Otsuka, Bunkyo-ku, Tokyo, Japan)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0490] Ibuprofen Ameliorates Differentiation Abnormalities of Oligodendrocyte Precursor Cells by HLD7-Associated POLR3A Mutant Proteins.

^○Sui Sawaguchi, Junji Yamauchi (Mol.Neurology.Lab., TUPLS)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0491] Generation and analysis of MECP2 mutant marmosets

^○Noriyuki Kishi^{1, 2}, Kenya Sato³, Junichi Hata^{1, 4}, Misako Okuno¹, Taeko Itou¹, Junko Okahara^{1, 3}, Hirotaka Okano^{1, 4}, Erika Sasaki^{1, 3}, Hideyuki Okano^{1, 2} (1.Lab. for M.N.A., RIKEN CBS, 2.Dept. of Physiology, Keio Univ. Med. of Sch., 3.CIEA, 4.Jikei Univ. Sch. of Med.)

The 44th Annual Meeting of the Molecular Biology Society of Japan