[2PWS2-06-4] Mutant p53 gain of function and SREBP-dependent cholesterol synthesis pathway in malignant characteristic of breast cancer

^○Tomoaki Tanaka (Dept. Mol. Diagnosis, Grad. Sch. of Med., Chiba Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 5:59 PM - 6:11 PM

[2PWS2-06-5] Polycomb-mediated DNA repair contributes to tumor suppression

^○Kyoichi Isono¹, Yayoi Kimura², Mami Kumon³, Takaho Endo⁴, Haruhiko Koseki³ (1.Lab. Anim. Ctr., Sch. of Med., Wakayama Med. Univ., 2.AMRC., Yokohama City Univ., 3.Lab. Dev. Genet., RIKEN IMS, 4.Lab. Integrative Genomics, RIKEN IMS)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:11 PM - 6:19 PM

[2PWS2-06-6] Mechanistic analysis of the colorectal cancer progression by MLL mutation and drug discovery for protein-protein interactions (PPIs) in MLL complex

^○Mitsuhiro Yoneda, Takeya Nakagawa, Naoko Hattori, Takashi Ito (Dept. of Biochem, Grad. Sch. of Biomed. Sci., Univ. of Nagasaki)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:19 PM - 6:27 PM

[2PWS2-06-7] SETD6 is methylation-silenced in gastric cancers despite resistance of most epigenetic regulators to aberrant methylation

^○Hideyuki Takeshima, Kazuhiro Nishiyama, Toshikazu Ushijima (Div. of Epigenomics, Natl.Cancer.Ctr.Res.Inst.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:27 PM - 6:35 PM

[2PWS2-06-8] Mitochondrial respiratory supercomplex assembly regulates metabolism and tumor growth

^○Kazuhiro Ikeda¹, Kuniko Horie¹, Satoshi Inoue^{1, 2} (1.Div. of Syst. Med. & Gene Ther., RCGM, Saitama Med. Univ., 2.Dept. of Syst. Aging Sci. and Med., Tokyo Metropolitan Inst. of Gerontol.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:35 PM - 6:47 PM

[2PWS2-06-9] Fluctuation of protein complex against various genome stresses

^○Tsuyoshi Ikura¹, Kanji Furuya², Takuma Shiraki³, Masae Ikura¹ (1.Lab. of Chromatin Regulatory Network, RBC, Div. of Systemic Life Science, Grad. Sch. of Biostudies, Kyoto Univ., 2.Lab. of Genome Maintenance, RBC, Div. of Systemic Life Science, Grad. Sch. of Biostudies, Kyoto Univ., 3.Kindai University, BOST)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:47 PM - 6:59 PM

[2PWS2-07-1] Effect of glycation on innate immune responses

^○Miho Chikazawa (Fac. of Agri., Meijo Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 5:31 PM - 5:53 PM

[2PWS2-07-2] Intracellular accumulation of advanced glycation end products induces osteoblast apoptosis via endoplasmic reticulum stress

^○Ryusuke Suzuki^{1, 2}, Yukio Fujiwara³, Mitsuru Saito¹, Shoutaro Arakawa¹, Junichi Shirakawa², Mikihiro Yamanaka², Yoshihiro Komohara³, Ryoji Nagai² (1.Dept. of Orthop. Surg., Jikei Univ., 2.Sch. of Agric., Tokai Univ., 3.Dept. of Cell path., Kumamoto Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 5:53 PM - 6:15 PM

[2PWS2-07-3] Addition of selenoglutathione to culture medium of the cells where the expression level of glyoxalase 1 is suppressed can restore the resistance to both glycation and oxidative stress

^○Akiko Kanamori^{1, 2, 3}, Sawa Takahashi¹, Saki Ohata¹, Shingo Shimodaira⁴, Michio Iwaoka⁴ (1.Dept. of Appl. Biochem., Sch. of Engineering, Tokai Univ., 2.Inst. Adv. Biosci., Tokai Univ., 3.Course of Appl. Sci., Grad. Sch. of Engineering, Tokai Univ., 4.Dept. of Chem., Sch. of Science, Tokai Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:15 PM - 6:37 PM

[2PWS2-07-4] Implication of AGEs-RAGE Signaling and Macrophage Polarization in the Pathogenesis of Diabetic Polyneuropathy

^○Sho Osonoi¹, Kazunori Sango², Hiroki Mizukami¹ (1.Dept. of Patho and Mol. Med., Grad. Sch. of Med., Univ. of Hirosaki, 2.Diabetic neuropathy project., TMiMS.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 2, 2021 6:37 PM - 6:59 PM