[1P-0572] GREB1 isoform 4 stimulates cell proliferation of malignant melanoma via pyrimidine synthesis

^○Koei Shinzawa¹, Shinji Matsumoto¹, Atsushi Tanemura², Kazunori Yokoi², Manabu Fujimoto², Keisuke Nimura³, Tomoyoshi Soga⁴, Akira Kikuchi¹ (1.Dept. Mol. Biol. and Biochem., Grad. Sch. Med., Osaka Univ., 2.Dept. Dermatol., Grad. Sch. Med., Osaka Univ., 3.Dept. Genome Biol., Grad. Sch. Med., Osaka Univ., 4.Inst. Adv. Biosci., Keio Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0573] Suppression of MKL1 promotes adipocytic differentiation and reduces the proliferation of myxoid liposarcoma cells

^○Kosuke Oikawa¹, Fuyuki Sato^{1, 2} (1.Dept. of Pathol., Wakayama Med. Univ., 2.Div. of Pathol., Shizuoka Cancer Center)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0574] Pan-cancer analysis of the association between mutation distribution in open chromatin region and patient prognosis

^○Chie Kikutake, Mikita Suyama (Division of Bioinformatics, MIB, Kyushu Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0575] Role of Mutant p53 on Malignancy of Brest Cancer Mediated by SREBP-dependent Mevalonate Pathway

^○Akitoshi Nakayama¹, Masataka Yokoyama¹, Hidekazu Nagano¹, Naoko Hashimoto¹, Kazuyuki Yamagata¹, Kazutaka Murata¹, Tohru Kiyono², Tomoaki Tanaka¹ (1.Dept. Mol. Diagnosis, Grad. Sch. of Med., Chiba Univ., 2.EPOC, Natl. Cancer Ctr.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0576] Suicide Gene Therapy Using Retroviral Replicating Vectors for Gastric Cancer

^○Hiroaki Fujino^{1, 2}, Emiko Sonoda¹, Lisa Isoda^{1, 3}, Ayane Kawabe^{1, 3}, Toru Takarada^{1, 4}, Noriyuki Kasahara⁵, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therapeutics, Advanced Med. Sci., Hyogo Col. of Med., 2.Dept. of Biosci., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 4.Lab. of Func. Mol. Chem., Kobe Pharm. Univ., 5.Dept. of Neurol. Surg. & Rad. Oncol., UCSF)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0577] Retroviral replicating vector-mediated suicide gene therapy for osteosarcoma

^○Ayane Kawabe^{1, 2}, Hiroaki Fujino^{1, 3}, Emiko Sonoda¹, Toru Takarada^{1, 4}, Noriyuki Kasahara⁵, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therapeutics, Advanced Med. Sci., Hyogo Col. of Med., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Dept. of Biosci., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 4.Lab. of Func. Mol. Chem., Kobe Pharm. Univ., 5.Dept. of Neurol. Surg. & Rad. Oncol., UCSF)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0578] Suicide gene therapy by retroviral replicating vectors for canine malignancies

^○Emiko Sonoda¹, Hiroaki Fujino^{1, 2}, Ayane Kawabe^{1, 3}, Toru Takarada^{1, 4}, Shunsuke Noguchi⁵, Noriyuki Kasahara⁶, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therapeutics, Advanced Med. Sci., Hyogo Col. of Med., 2.Dept. of Biosci., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 4.Lab. of Func. Mol. Chem., Kobe Pharm. Univ., 5.Lab. of Veterinary Radiol, Graduate Sch. of Life & Environ. Sci., Osaka Prefecture Univ., 6.Dept. of Neurol. Surg. & Rad. Oncol., UCSF)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0579] Pharmacological inhibition of Mint3-FIH-1 interaction attenuates tumour growth, metastasis, and endotoxic shock in in vitro and in vivo analyses

^○Takeharu Sakamoto^{1, 2}, Yuya Fukui^{2, 3}, Yasumitsu Kondoh⁴, Kaori Honda⁴, Takeshi Shimizu⁴, Toshiro Hara⁵, Tetsuro Hayashi⁶, Yurika Saitoh⁷, Yoshinori Murakami⁶, Junichiro Inoue³, Shuichi Kaneko², Hiroyuki Osada⁴, Motoharu Seiki⁵ (1.Dept. Cancer Biol., Inst. Biomed. Sci., Kansai Medical Univ., 2.Dept. System Biol., Inst. Med., Pharm., and Health Sci., Kanazawa Univ., 3.Div. Cell. Mol. Biol., Inst. Med. Sci., Univ. of Tokyo, 4.Chem. Biol. Res. Group, RIKEN Cent. Sustainable Res. Sci., 5.Div. Cancer Cell Res., Inst. Med. Sci., Univ. of Tokyo, 6.Div. Mol. Path., Inst. Med. Sci., Univ. of Tokyo, 7.Cent. Med. Edu., Teikyo Univ. of Science)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0580] Prognosis prediction by the genes associated with cancer morphology and microenvironment in primary central nervous system lymphoma

^○Yasuo Takashima^{1, 2}, Atsushi Kawaguchi³, Junya Fukai⁴, Yasuo Iwadate⁵, Koji Kajiwara⁶, Hiroaki Hondoh⁷, Ryuya Yamanaka^{1, 2} (1.Osaka Iseikai Clinic for Cancer Therapy, 2.Lab. of Mol. Target Therapy for Cancer, Grad. Sch. of Med. Sci., Kyoto Pref. Univ. of Med., 3.Center for Comprehensive Community Medicine, Fac. of Med., Saga Univ., 4.Dept. of Neurological Surgery, Wakayama Med. Univ. Sch. of Med., 5.Dept. of Neurosurgery, Grad. Sch. of Med. Sci., Chiba Univ., 6.Dept. of Neurosurgery, Grad. Sch. of Med. Sci., Yamaguchi Univ., 7.Dept. of Neurosurgery, Toyama Pref. Central Hospital)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0581] Spatial transcriptome and genomic mutation analysis for elucidating cell diversity in cancer microenvironment of non-small cell lung cancer after EGFR-TKI treatment

^○Miki Yamazaki^{1, 2}, Hiroko Matsunaga³, Masahito Hosokawa^{1, 3}, Koji Arikawa³, Naoko Suzuki³, Takuo Hayashi⁴, Haruko Takeyama^{1, 2, 3, 5} (1.Grad. Sch. Adv. Sci. Eng., Waseda Univ., 2.CBBD-OIL, AIST-Waseda Univ., 3.Res. Org. Nano Life Innov., Waseda Univ., 4.Dept. Human Pathol., Grad. Sch. Med., Juntendo Univ., 5.Inst. Adv. Res. Biosyst. Dyn., Waseda Res. Inst. Sci. Eng., Waseda Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan