[1AW-13-1] BCAA metabolism regulates stem cell fates in cancer

^○Takahiro Ito (Inst Front Life Med Sci, Kyoto Univ)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:01 AM - 9:26 AM

[1AW-13-2] Leucine uptake is essential for the growth of ER+ breast cancer cells under nutrient stress

^○Yasuhiro Saito (Inst. of Adv. Biosci., Keio Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:26 AM - 9:51 AM

[1AW-13-3] Human acute leukemia utilizes branched-chain amino acid catabolism to maintain their stemness through regulating PRC2 function

^○Yoshikane Kikushige (Center for Cellular and Molecular Medicine, Kyushu University Hospital)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:51 AM - 10:16 AM

[1AW-13-4] BCAA catabolism controls energy homeostasis

^○Takeshi Yoneshiro (Div. Metab. Med., RCAST, Univ. of Tokyo)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 10:16 AM - 10:41 AM

[1AW-13-5] The regulatory roles of branched-chain amino acid metabolites in pyruvate metabolism

^○Kiyoto Nishi^{1, 2}, Eiichiro Nishi¹, Rong Tian² (1.Dept. of Pharmacol., Shiga Univ. of Med. Sci., 2.Dept. of APM, Univ. of Washington)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 10:41 AM - 10:58 AM

[1AW-13-6] Modulation of Cellular Senescence by Branched-Chain Amino Acid Metabolism

^○Akimitsu Konishi¹, Yuma Aramaki¹, Hideru Obinata², Shinya Honda³, Takashi Izumi⁴, Shigeomi Shimizu³, Yoji Minamishima¹ (1.Dept. of Biol. Grad. Sch. of Med. Gunma Univ., 2.ERSC Grad. Sch. of Med. Gunma Univ., 3.Dept. of Path. Cell Biol. Med. Res. Inst. TMDU, 4.Fac. of Health Care, Teikyo Heisei Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 10:58 AM - 11:15 AM

[1AW-14-1] A mannosidase in the endoplasmic reticulum exerts its function by protein-protein association

^○Satoshi Ninagawa¹, Ginto George¹, Hirokazu Yagi², Junichi Furukawa³, Noritaka Hashii⁴, Akiko Ishii⁴, Ying Deng¹, Tokiro Ishikawa¹, Koshi Imami⁵, Yasushi Ishihama⁵, Koichi Kato^{2, 6}, Tetsuya Okada¹, Kazutoshi Mori¹ (1.Dept. of Biophys., Grad. Sch. of Sci., Univ. of Kyoto, 2.Dept. of Struct. Biol., Grad. Sch. of Pharm Sci., Univ. of Nagoya city, 3.Dept. of Struct. Biol., Grad. Sch. of Medi., Univ. of Hokkaido, 4.Div. of Biol. Chem. & Biol., Nat. Inst. of Heal. Sci., 5.Dept. of Mole. & Cellu. BioA., Grad. Sch. of Pharm. Sci., Univ. of Kyoto, 6.ExCELLS & Inst. for Mole. Sci., Nati. Inst. of Natu. Sci.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:03 AM - 9:21 AM

[1AW-14-2] Ferritin forms a liquid-like condensate that becomes a common substrate for macro-autophagy and endosomal micro-autophagy

Tomoko Ohshima¹, ^○Hayashi Yamamoto¹, Yuriko Sakamaki², Chieko Saito¹, Noboru Mizushima¹ (1.Graduate School of Medicine, The University of Tokyo, 2.Research Core, Tokyo Medical and Dental University)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:21 AM - 9:31 AM

[1AW-14-3] Elucidating the ER protein quality control mechanism by assembled PDI family, the ER-resident enzyme/chaperones

^○masaki okumura (FRIS, Tohoku Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:31 AM - 9:49 AM

[1AW-14-4] Single-molecule observation of the effects of Hero proteins on TDP-43 conformation

^○Andy Lam^{1, 2}, Kotaro Tsuboyama^{1, 3}, Hisashi Tadakuma^{1, 4}, Yukihide Tomari^{1, 2} (1.Inst. for Quant. Biosci., Univ. of Tokyo, 2.Dept. of Comp. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 3.Dept. of Pharmacol., Northwestern Univ., 4.Sch. of Life. Sci. and Tech., ShanghaiTech Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 1, 2021 9:49 AM - 9:59 AM